Heart Health / Cholesterol SupportPlant Sterols & Stanols1800mg DailyUSP VerifiedGluten-FreeHeart Health

Full Review: Nature Made CholestOff Plus – Plant Sterols Supplement (100 Softgels)

Dmitry PetrovNutritionist
6 min
January 15, 2026
4.5(5163 reviews)
Full Review: Nature Made CholestOff Plus – Plant Sterols Supplement (100 Softgels)

Short Summary

Clinically proven plant sterol supplement to help reduce dietary cholesterol absorption and support heart health as part of a low-fat diet.

Pros

  • +Effective at lowering LDL/total cholesterol for many users
  • +Natural alternative or complement to diet/exercise
  • +USP verified quality
  • +No artificial additives
  • +Good value for heart-focused supplement

Cons

  • -Large softgels hard to swallow for some
  • -Potential mild stomach issues
  • -Results vary; not effective for everyone
  • -Capsules may stick together in storage

Ingredients & Formula

Phytosterols (plant sterols/stanols esters, 900mg per serving), gelatin, soybean oil, etc.

Who It’s For

Adults managing cholesterol levels through diet, seeking natural support for heart health.

How to Take

2 softgels twice daily with largest meals and water.

Quality & Enjoyment

#1 pharmacist recommended brand with clinical backing.

What to Watch Out For

Consult doctor if on cholesterol meds, pregnant, or have soy allergy. Part of low-sat fat diet needed.

DP

Dmitry Petrov

Nutritionist

PhD in Biology, sports nutrition specialist with 15 years of experience

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